abstract：BACKGROUND:The prognostic significance of red cell distribution width (RDW) during hospitalization in internal medicine wards was not sufficiently investigated. METHODS:Demographic, clinical and laboratory characteristics were collected from 586 internal medicine inpatients. Following discharge, all-cause mortality wa...

journal_title：European journal of internal medicine

authors： Shteinshnaider M,Barchel D,Almoznino-Sarafian D,Tzur I,Tsatsanashvili N,Swarka M,Cohen N,Gorelik O

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The use of commercially available noninvasive markers for chronic hepatitis B (CHB) related fibrosis is not widely available in developing countries so clinicians in those countries frequently use free alternatives. We aimed to create an optimized algorithm for selection of patients with the highest probabili...

journal_title：European journal of internal medicine

authors： Salkic NN,Cickusic E,Jovanovic P,Denjagic MB,Iljazovic-Topcic S,Bevanda M,Ahmetagic S

更新日期：2015-10-01 00:00:00

abstract：:The belief that hospital stays may constitute per se a risk for patients is not widespread among patients and health care professionals. In the balance between advantages and disadvantages of admission, we rarely take into account the impact of the hospital stay itself on the well-being of the patient. In a society th...

journal_title：European journal of internal medicine

authors： Sbrojavacca R,Pietrangelo A,Fenoglio L,Violi F,Perticone F,Corazza GR

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Patients admitted to general internal medicine wards might receive a large number of drugs and be at risk for drug-related problems (DRPs) associated with increased morbidity and mortality. This study aimed to detect suboptimal drug use in internal medicine by a pharmacotherapy evaluation, to suggest treatme...

journal_title：European journal of internal medicine

authors： Guignard B,Bonnabry P,Perrier A,Dayer P,Desmeules J,Samer CF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Whether diabetes mellitus (DM) is associated with a higher risk of perioperative mortality and mortality after liver transplantation (LTx) remains unclear. METHODS:We compared the risk of postoperative mortality and morbidity in DM and non-DM patients undergoing LTx. We enrolled 558 DM patients who underwen...

journal_title：European journal of internal medicine

authors： Tsai MS,Wang YC,Wang HH,Lee PH,Jeng LB,Kao CH

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:According to Swiss legislation, do not attempt cardiopulmonary resuscitation (DNACPR) order can be made at any time by patients only, unless the resuscitation is considered as futile, based on the doctors' evaluation. Little is known about how this decision is made, and which are the factors influencing this...

journal_title：European journal of internal medicine

authors： Chevaux F,Gagliano M,Waeber G,Marques-Vidal P,Schwab M

更新日期：2015-06-01 00:00:00

abstract：:Recent large epidemiological studies have confirmed that an elevated resting heart rate is an independent predictor of cardiovascular and overall mortality in the general population as well as in patients with hypertension, coronary heart disease and chronic heart failure. Pathophysiological studies indicate that a hi...

journal_title：European journal of internal medicine

authors： Caetano J,Delgado Alves J

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Hospitals are under pressure to use resources in the most efficient manner. We have examined the factors predicting Length of Stay (LOS) in one institution, using a database of all episodes of emergency medical admissions prospectively collected over 12 years. AIM:To examine the ability to predict hospital ...

journal_title：European journal of internal medicine

authors： Cournane S,Byrne D,O'Riordan D,Silke B

更新日期：2015-05-01 00:00:00

abstract：INTRODUCTION:Patients with chronic hepatitis C (CHC) and end-stage renal disease (ESRD) on dialysis are difficult to treat and show higher dropout rates during treatment. The aim of this study was to analyze the treatment outcomes in patients with CHC and underlying end-stage renal disease on dialysis in Korea. METHOD...

journal_title：European journal of internal medicine

authors： Ahn SB,Jun DW,Kim SG,Lee SH,Shin HP,Choe WH,Kim JK,Jung KS,Kim DY,Shim JJ,Park SY,Seo YS,Kim W,Chung JI

更新日期：2015-05-01 00:00:00

abstract：:Erdheim-Chester disease (ECD) is rare form of non-Langerhans cells histiocytosis with multiorgan involvement. Individuals are more frequently affected in their fifth decade and there is a slight male prevalence. Recent studies have demonstrated that ECD patients bare mutations in the proto-oncogene BRAF (and more rare...

journal_title：European journal of internal medicine

authors： Campochiaro C,Tomelleri A,Cavalli G,Berti A,Dagna L

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Multimorbidity is a huge burden to individuals and societies and more attention should be paid on its risk factors and prevention possibilities. The aim of this study was to investigate which clinical and lifestyle characteristics predict the development of multimorbidity both among initially disease-free pe...

journal_title：European journal of internal medicine

authors： Wikström K,Lindström J,Harald K,Peltonen M,Laatikainen T

更新日期：2015-04-01 00:00:00

abstract：:Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing...

journal_title：European journal of internal medicine

authors： Onder G,Palmer K,Navickas R,Jurevičienė E,Mammarella F,Strandzheva M,Mannucci P,Pecorelli S,Marengoni A,Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS).

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Diagnostic algorithms for pulmonary embolism (PE) have been validated in patients attending hospital emergency departments. However, general practitioners (GPs) are often the professionals of first resort for the majority of non-critical cases of PE. AIM:To evaluate the knowledge of the diagnostic algorithm...

journal_title：European journal of internal medicine

authors： Planquette B,Maurice D,Peron J,Mourin G,Ferre A,Sanchez O,Meyer G

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Fatty pancreas (FP) is related to obesity, and may have some clinical implications on glucose metabolism. The frequency and importance of FP in patients with nonalcoholic steatohepatitis (NASH) are not clear. This study aimed to investigate: the frequency of FP in patients with NASH, and its effects on serum ...

journal_title：European journal of internal medicine

authors： Uygun A,Kadayifci A,Demirci H,Saglam M,Sakin YS,Ozturk K,Polat Z,Karslioglu Y,Bolu E

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic diseases often receive multiple medications and are associated with increased vulnerability to medication errors. Identifying high-alert medications for them would help to prioritize the interventions with greatest impact for improving medication safety. The aim of this study was to dev...

journal_title：European journal of internal medicine

authors： Otero MJ,Moreno-Gómez AM,Santos-Ramos B,Agra Y

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND/AIMS:Current results had demonstrated lamivudine (LAM) contributed to improve liver function and short-term prognosis in patients with hepatitis B virus-related acute-on-chronic liver failure (ACLF), but data concerning the outcome of long-term prognosis are limited. Our objective was to explore the predicti...

journal_title：European journal of internal medicine

authors： Xiang-Hui Y,Lang X,Yan Z,Li Z,Xiao-Feng S,Hong R

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Many activities contribute to reduce drug-related problems. Among them, the medication reconciliation (MR) is used to compare the best possible medication history (BPMH) and the current admission medication order (AMO) to identify and solve unintended medication discrepancies (UMD). This study aims to assess...

journal_title：European journal of internal medicine

authors： Leguelinel-Blache G,Arnaud F,Bouvet S,Dubois F,Castelli C,Roux-Marson C,Ray V,Sotto A,Kinowski JM

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To analyze the incidence of VTE in hospitalized medical patients and prophylaxis applied in accordance with the 8th ACCP guidelines and the National PRETEMED guide for thromboprophylaxis. METHODS:Discharge lists were reviewed to select the first consecutive 20 patients, aged ≥ 40 years and admitted ≥ 4 days ...

journal_title：European journal of internal medicine

authors： Nieto JA,Cámara T,Camacho I,MEDITROM Investigators.

更新日期：2014-10-01 00:00:00

abstract：INTRODUCTION/AIM:Patients who present HBV reactivation during immunosuppressive treatment are prone to develop life threatening decompensation of the liver function, therefore prophylaxis and treatment are strongly recommended. So far there are no data regarding the role of tenofovir in this context. Therefore, the aim...

journal_title：European journal of internal medicine

authors： Koskinas JS,Deutsch M,Adamidi S,Skondra M,Tampaki M,Alexopoulou A,Manolakopoulos S,Pectasides D

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Patients with multiple myeloma (MM) manifesting acute kidney injury (AKI) and who later recover renal function and independence from renal replacement therapy (RRT) are considered to have a better outcome. The aim of this work was to study the factors associated with renal function recovery (independence of ...

journal_title：European journal of internal medicine

authors： Rodrigues L,Neves M,Sá H,Gomes H,Pratas J,Campos M

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:There is some evidence to suggest that exercise systolic blood pressure (SBP) may be associated with future risk of stroke in subjects without a history of coronary artery disease (CAD). However, the value of an exaggerated exercise SBP response (EESBPR) for predicting stroke in patients referred ...

journal_title：European journal of internal medicine

authors： Bouzas-Mosquera Mdel C,Bouzas-Mosquera A,Peteiro J,Broullón FJ,Alvarez-García N,Castro-Beiras A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Few data on patterns of care and outcomes are available for elderly patients with diffuse large B-cell lymphoma (DLBCL) outside of clinical trials. METHODS:We identified patients with DLBCL older than 60 years from a regional cancer registry between 2000 and 2010. Based on registry data and chart review, 12...

journal_title：European journal of internal medicine

authors： Diem S,Ess S,Cerny T,Früh M,Hitz F

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND & AIMS:Non-alcoholic fatty liver disease was traditionally interpreted as a condition which may progress to liver-related complications. However, the increased mortality is primarily a result of cardiovascular diseases. It has been suggested that fatty liver can be considered as the hepatic consequence of th...

journal_title：European journal of internal medicine

authors： Del Ben M,Polimeni L,Brancorsini M,Di Costanzo A,D'Erasmo L,Baratta F,Loffredo L,Pastori D,Pignatelli P,Violi F,Arca M,Angelico F

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Infliximab (IFX) and adalimumab (ADA) are the key treatments for Crohn's Disease (CD), unresponsive to standard treatments. Our aim was to compare the efficacy and safety of IFX and ADA in treating CD in clinical practice. METHODS:One hundred and twenty-six patients (61 M, 65 F, mean age 36.2 years, range 1...

journal_title：European journal of internal medicine

authors： Tursi A,Elisei W,Picchio M,Penna A,Lecca PG,Forti G,Giorgetti G,Faggiani R,Zampaletta C,Pelecca G,Brandimarte G

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:This study investigated the correlation between Helicobacter pylori (HP) and cancer risk. We compared the age, sex, and comorbidity of cancer patients both infected and not infected by HP. METHODS:In this study, we compared a comparison cohort (N=24,088) and an HP cohort (N=6022), both taken from the NHI da...

journal_title：European journal of internal medicine

authors： Hsu WY,Lin CH,Lin CC,Sung FC,Hsu CP,Kao CH

更新日期：2014-03-01 00:00:00

abstract：:The morbidity and mortality related to many communicable infectious diseases have significantly decreased in Western countries largely because of the use of antibiotics, and the implementation of well-planned vaccination strategies and national immunisation schedules specifically aimed at infants and children. However...

journal_title：European journal of internal medicine

authors： Esposito S,Durando P,Bosis S,Ansaldi F,Tagliabue C,Icardi G,ESCMID Vaccine Study Group (EVASG).

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The aims of this study were to evaluate the quality of oral anticoagulation (OAC) in AF patients in the practices of general practitioners (GPs) in Germany and to investigate possible causal factors which influence OAC quality. METHODS:We conducted a multi-center, non-interventional, prospective observation...

journal_title：European journal of internal medicine

authors： Mueller S,Pfannkuche M,Breithardt G,Bauersachs R,Maywald U,Kohlmann T,Wilke T

更新日期：2014-03-01 00:00:00

abstract：:CHF is a disease of high incidence and prevalence in the elderly. Anemia is associated with an increased mortality in these patients. Erythropoietin secretion is reduced in these patients due to complexed mechanisms. Although some improvement in quality of life has been shown when using ESAs it has not been found any ...

journal_title：European journal of internal medicine

authors： Robles NR,Macias JF,Herrera J

更新日期：2014-02-01 00:00:00

abstract：:Stroke is the most frequent neurological disease and represents a continuously evolving medical and social problem. Chronic kidney disease (CKD) is also an important worldwide public health problem. Renal dysfunction carries a substantial risk of cardiovascular morbidity and mortality and an independent, graded associ...

journal_title：European journal of internal medicine

authors： Hojs Fabjan T,Hojs R

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although a decreasing trend of tuberculosis (TB) was reported in Turkey, higher proportion of extrapulmonary tuberculosis (EPT) was revealed. MATERIAL AND METHODS:In this retrospective study, clinical and laboratory data of 141 EPT patients were evaluated for a seven-year period by using descriptive statist...

journal_title：European journal of internal medicine

authors： Sevgi DY,Derin O,Alpay AS,Gündüz A,Konuklar AS,Bayraktar B,Bulut E,Uzun N,Sonmez E

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The prognostic significance of hypoalbuminemia and the dynamic changes in serum albumin during hospitalization in internal medicine wards has not been sufficiently investigated. METHODS:Demographic, clinical and laboratory data were collected from 276 patients admitted to our internal medicine ward for a va...

journal_title：European journal of internal medicine

authors： Barchel D,Almoznino-Sarafian D,Shteinshnaider M,Tzur I,Cohen N,Gorelik O

更新日期：2013-12-01 00:00:00

abstract：:Human serum albumin (HSA) is the most abundant circulating protein and accounts for about 70% of the plasma colloid osmotic pressure. Beside the well known capacity to act as plasma-expander, HSA is provided of many other properties which are unrelated to the regulation of fluid compartmentalization, including binding...

journal_title：European journal of internal medicine

authors： Caraceni P,Domenicali M,Tovoli A,Napoli L,Ricci CS,Tufoni M,Bernardi M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Melatonin exerts multiple biological effects with potential impact on human diseases. This is underscored by genetic studies that demonstrated associations between melatonin receptor type 2 gene (MTNR1B) polymorphisms and characteristics of type 2 diabetes. We set out to test the hypothesis whether genetic v...

journal_title：European journal of internal medicine

authors： Huber M,Treszl A,Reibis R,Teichmann C,Zergibel I,Bolbrinker J,Scholze J,Wegscheider K,Völler H,Kreutz R

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to characterize the common risk factors, clinical presentation, imaging findings, treatment and outcome of nocardial infection. DESIGN AND SETTINGS:A retrospective cohort study. We reviewed the charts of all patients with nocardiosis in the Chaim Sheba Medical Center, a tertia...

journal_title：European journal of internal medicine

authors： Rosman Y,Grossman E,Keller N,Thaler M,Eviatar T,Hoffman C,Apter S

更新日期：2013-09-01 00:00:00

abstract：:There is growing evidence suggesting a causative relationship between adrenal adenomas and metabolic and cardiovascular deteriorations. Although demonstrated frequently in subjects with subclinical Cushing Syndrome, subjects with non-functioning adrenal adenomas feature a variety of metabolic and cardiovascular conseq...

journal_title：European journal of internal medicine

authors： Yener S

更新日期：2013-09-01 00:00:00

abstract：:Atypical hemolytic uremic syndrome (aHUS) is a devastating form of renal thrombotic microangiopathy. In the last five years, we have finally witnessed a dramatic improvement in the management of aHUS patients, and three breakthroughs in our understanding of aHUS have led to such an improvement. The first breakthrough ...

journal_title：European journal of internal medicine

authors： Fakhouri F,Frémeaux-Bacchi V,Loirat C

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Prognostic implications of echocardiographic assessment of pulmonary hypertension (PH) in non-selected patients hospitalized for acute heart failure (AHF) are not clearly defined. The aim of this study was to evaluate the association between echocardiography-derived PH in AHF and 1-year all-cause mortality. ...

journal_title：European journal of internal medicine

authors： Merlos P,Núñez J,Sanchis J,Miñana G,Palau P,Bodí V,Husser O,Santas E,Bondanza L,Chorro FJ

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Granulomas in bone marrow are an infrequent finding related to various disorders. The aim of this study was to review our clinical experience with granulomatous bone marrow disease and to describe the contributions of recent diagnostic tools, such as (18)F-Fluorodeoxyglucose positron emission tomography ((18)F-...

journal_title：European journal of internal medicine

authors： Brackers de Hugo L,Ffrench M,Broussolle C,Sève P

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The aims of the present study were to determine both clinical manifestations and outcome of anti-PL7 patients with antisynthetase syndrome (ASS). METHODS:The medical records of 15 consecutive anti-PL7 patients with biopsy proven ASS were retrospectively analyzed without prior selection. RESULTS:Anti-PL7 pa...

journal_title：European journal of internal medicine

authors： Marie I,Josse S,Decaux O,Diot E,Landron C,Roblot P,Jouneau S,Hatron PY,Hachulla E,Vittecoq O,Menard JF,Jouen F,Dominique S

更新日期：2013-07-01 00:00:00

abstract：:The need for anticoagulation in patients with atrial fibrillation (AF), and the inherent limitations of warfarin have fostered the search for direct oral anticoagulant drugs (DOACs). In recent years, inhibitors of thrombin (Dabigatran etexilate) and of activated factor X (Rivaroxaban, Apixaban) have become clinically ...

journal_title：European journal of internal medicine

authors： Di Minno G,Russolillo A,Gambacorta C,Di Minno A,Prisco D

更新日期：2013-06-01 00:00:00